YAMAMOTO RESEARCH GLR Stick Setria® Orosolubile 30 sticks

Yamamoto® Research’s Setria® GLR Orosoluble Sticks is a dietary supplement in orosoluble stick form that provides 250 mg per daily dose of Setria® Reduced L-Glutathione. Glutathione is a potent antioxidant molecule that plays a key role in protecting the body against oxidative stress and the action of free radicals and is able to protect the hepatocytes against toxic molecules that can cause liver damage. The formulation in a handy orosoluble sticks ensures rapid dissolution and sublingual absorption, enabling the body to quickly and optimally absorb Glutathione from the sublingual venous circulation tributary to the superior vena cava, thus bypassing intestinal gamma-glutamyltransferase activity and avoiding the metabolic avidity of the enterocytes. It therefore escapes the *hepatic filter** and avoids the first-pass metabolism that usually takes place in the liver and deactivates a significant part of the glutathione molecule, thus making it less functional and effective. One of our first lines of defence is Glutathione, a ubiquitous molecule, i.e. one that is present throughout our body, but that is particularly concentrated in the liver, where it protects liver cells from toxic molecules: in this case, Glutathione “binds” to and neutralises toxic metabolites. Reduced glutathione is in fact able to surrender its hydrogen (H+), which acts as an acceptor of electrons (e-) from reactive oxygen molecules, i.e. free radicals. At this point, having eliminated the danger caused by free radicals, glutathione can regain its antioxidant activity and return to its reduced form. Glutathione’s ability to continually regenerate itself is the reason why it is considered the most powerful antioxidant in the human body. The molecule's biological functions support its clinical utility in several situations, foremost among them its ability to protect the liver against the action of toxic substances. In the past, the oral intake of glutathione was the limiting factor for its use in food supplements, as the human gut contains significant amounts of the enzyme gamma-glutamyltranspeptidase, which is responsible for the degradation of glutathione after oral ingestion. Consequently, the molecule was only truly effective when injected. Thanks to the special absorption route of Setria® GLR Orosoluble Sticks, a next-generation reduced glutathione supplement in a handy orosoluble stick form, it is possible to bypass the enzymatic steps responsible for the molecule's loss of effectiveness and ensure the body optimal bioavailability of glutathione.

• Formulation handy orosoluble stick form for rapid absorption
• Counteracts free radicals and helps remove toxins
• Promotes liver and gastrointestinal function
• 250 mg of Setria®-quality reduced L-glutathione per capsule
• Promotes the regeneration and reactivation of other antioxidants